| Item | Value |
|---|---|
| DrugBank ID | DB00056 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 15 |
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | acute myeloid leukemia with NPM1 somatic mutations | TxGNN Knowledge Graph |
| 2 | acute myeloid leukemia with t(6;9)(p23;q34) | TxGNN Knowledge Graph |
| 3 | unclassified acute myeloid leukemia | TxGNN Knowledge Graph |
| 4 | acute myeloblastic leukemia with maturation | TxGNN Knowledge Graph |
| 5 | acute myeloid leukemia with minimal differentiation | TxGNN Knowledge Graph |
| 6 | acute myeloblastic leukemia without maturation | TxGNN Knowledge Graph |
| 7 | myeloid leukemia | TxGNN Knowledge Graph |
| 8 | inherited acute myeloid leukemia | TxGNN Knowledge Graph |
| 9 | acute myeloid leukemia with t(8;16)(p11;p13) translocation | TxGNN Knowledge Graph |
| 10 | acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2) | TxGNN Knowledge Graph |
| 11 | acute myeloid leukemia with t(9;11)(p22;q23) | TxGNN Knowledge Graph |
| 12 | acute myeloid leukemia with CEBPA somatic mutations | TxGNN Knowledge Graph |
| 13 | therapy related acute myeloid leukemia and myelodysplastic syndrome | TxGNN Knowledge Graph |
| 14 | acute myeloid leukemia with t(8;21)(q22;q22) translocation | TxGNN Knowledge Graph |
| 15 | acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor | TxGNN Knowledge Graph |
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.